Bone Engineering Using Human Demineralized Dentin Matrix and Recombinant Human BMP-2
نویسندگان
چکیده
منابع مشابه
Bone Engineering Using Human Demineralized Dentin Matrix and Recombinant Human BMP-2
We first confirmed the osteoinductive property of human demineralized dentin matrix (DDM) histologically. Human DDM was prepared from vital, extracted teeth and implanted into the subcutaneous tissue in nude mice. The shape of the DDM was a particle type and its size varied from 0.4 to 0.8 mm. The hard tissue induction by 70 mg of the DDM was estimated at 4 weeks after implantation. The DDM ind...
متن کاملDemineralized dentin matrix combined with recombinant human bone morphogenetic protein-2 in rabbit calvarial defects
OBJECTIVES The aim of this study was to compare the osteogenic effects of demineralized dentin matrix (DDM) combined with recombinant human bone morphogenetic protein-2 (rhBMP-2) in rabbit calvarial defects with DDM and anorganic bovine bone (ABB) combined with rhBMP-2. MATERIALS AND METHODS Four round defects with 8-mm diameters were created in each rabbit calvaria. Each defect was treated w...
متن کاملEvaluation of the Healing Potential of Demineralized Dentin Matrix Fixed with Recombinant Human Bone Morphogenetic Protein-2 in Bone Grafts
We aimed to evaluate the efficacy of demineralized dentin matrix (DDM) fixed with recombinant human bone morphogenetic protein-2 (rhBMP-2) through an experimental and a clinical study. Unilateral upper second and third premolars of eight beagles were extracted. A mucoperiosteal flap was elevated around the extraction socket, and a bone defect was made using a surgical drill. Each DDM was fixed ...
متن کاملDemineralized dentin matrix scaffolds for alveolar bone engineering
From the point of view of implant dentistry, this review discusses the development and clinical use of demineralized dentin matrix (DDM) scaffolds, produced from the patient's own extracted teeth, to repair alveolar bone defects. The structure and the organic and inorganic components of DDM are presented to emphasize the similarities with autogenous bone. Studies of DDM properties, such as oste...
متن کاملBone Induction by Demineralized Dentin Matrix in Nude Mouse Muscles
PURPOSE This study examined the osteoinductive activity of demineralized human dentin matrix for nude mice. METHODS Twenty healthy nude mice weighing about 15 to 20 g were used for study. Demineralized human dentin matrix was prepared and implanted into the dorsal portion of nude mice (subcutaneous), which were sacrificed at two, four, and eight weeks after demineralized dentin matrix graftin...
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ژورنال
عنوان ژورنال: Journal of Hard Tissue Biology
سال: 2005
ISSN: 1341-7649
DOI: 10.2485/jhtb.14.80